The FDA has approved the use of Sculptra Aesthetic long acting facial filler that builds collagen. Sculptra Aesthetic (injectable poly-L-lactic acid) has been approved for use by a trained physician to correct shallow to deep nasolabial fold (smile lines) contour deficiencies and other facial wrinkles. The injectable dermal filler works gradually to offer natural-looking results that can last up to two years. The treatment was available in Europe for a decade.